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American Cruise Lines

Baltimore Cruise Guide > Cruise Ships > American Cruise Line

American Cruises from Baltimore

American Cruise Lines offers coastal cruises on modern ships. The small ships are able to navigate America's smooth, inland waterways and dock in untraveled ports. American Cruise Line itineraries let you experience each area's local culture, history and natural beauty.

Take one of the American Cruise Line small ships on a cruise from Baltimore to the little towns of the Chesapeake Bay. Or sail down the east coast on the protected waters of the Intracoastal Waterway.

American's small ship cruises feature friendly all-American crew. Skilled chefs prepare feasts that highlight the flavors of the regions you'll visit. Enjoy complimentary cocktails and hors d'oeuvres before dinner. Dining is informal and you can sit with whomever you like. Each table has an outside view, so take your time and savor your cooked-to-order meal.

All staterooms face outside and are the largest in their class - featuring private baths and large, opening picture windows. Some staterooms also have private balconies.

Chesapeake Bay

7-night Chesapeake Bay cruises on American Cruise Lines. Round-trip from Baltimore to Yorktown (Virginia), Williamsburg (Virginia), St Michaels (Maryland) and Annapolis (Maryland).
• 2026 departures: April 10, April 17, April 24, May 15, May 31, October 1, October 8, October 29.
• 2027 departures: May 11, May 18, May 25, May 28, June 1, September 16, September 23, October 14, October 21.

Potomac River & Chesapeake Bay

7-night Potomac River & Chesapeake Bay cruises on American Cruise Lines. One-way from Baltimore to Washington (DC). Visit Annapolis (Maryland), St Michaels (Maryland), Cambridge (Maryland), Williamsburg (Virginia) and Mount Vernon (Virginia).
• 2026 departures: May 1, October 15.
• 2027 departures: May 14, September 30, November 14.

East Coast

14-night East Coast Inland Passage cruise on American Cruise Lines. One-way from Baltimore to Amelia Island (Florida). Visit St Michaels (Maryland), Norfolk (Virginia), Kitty Hawk (North Carolina), Beaufort (North Carolina), Wilmington (North Carolina), Charleston (South Carolina), Beaufort (South Carolina), Hilton Head (South Carolina), Savannah (Georgia), St Simons Island (Georgia), Jekyll Island (Georgia) and Fernandina Beach (Florida).
• 2026 departures: October 26, October 31, November 3, November 4.
• 2027 departures: October 25, November 8, November 17.

American Cruise Lines
Chesapeake Bay Cruise
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